Journal article
Cerebral palsy: Early markers of clinical phenotype and functional outcome
C Einspieler, AF Bos, M Krieber-Tomantschger, E Alvarado, VM Barbosa, N Bertoncelli, M Burger, O Chorna, S Del Secco, RA Deregnier, B Hüning, J Ko, L Lucaccioni, T Maeda, V Marchi, E Martín, C Morgan, A Mutlu, A Nogolová, J Pansy Show all
Journal of Clinical Medicine | Published : 2019
DOI: 10.3390/jcm8101616
Abstract
The Prechtl General Movement Assessment (GMA) has become a cornerstone assessment in early identification of cerebral palsy (CP), particularly during the fidgety movement period at 3–5 months of age. Additionally, assessment of motor repertoire, such as antigravity movements and postural patterns, which form the Motor Optimality Score (MOS), may provide insight into an infant’s later motor function. This study aimed to identify early specific markers for ambulation, gross motor function (using the Gross Motor Function Classification System, GMFCS), topography (unilateral, bilateral), and type (spastic, dyskinetic, ataxic, and hypotonic) of CP in a large worldwide cohort of 468 infants. We fo..
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Grants
Awarded by Japan Society for the Promotion of Science
Funding Acknowledgements
Magdalena Krieber-Tomantschger was supported by the OeNB (Oesterreichische Nationalbank, P16430), the City of Graz, and the Austrian Ophthalmological Society (Dr. Adele Rabensteiner Preis); Olena Chorna, Sabrina Del Secco, and Viviana Marchi were supported by Ricerca corrente for the IRCCS (2019) funded by the Italian Ministry of Health, IRCCS, Fondazione Stella Maris 2019, the American Academy for Cerebral Palsy & Developmental Medicine and The Cerebral Palsy Alliance (RG 2017), and the Mariani Foundation for Paediatric Neurology (R15-96); Raye-Ann DeRegnier by Friends of Prentice; Tomoki Maeda by JSPS KAKENHI (Grant Number 15K11705 and 18K10748); Catherine Morgan by the Australasian Cerebral Palsy Clinical Trials Network (AusCP-CTN, NHMRC NUMBER 1116442); Alicia Spittle by National Health and Medical Research Council of Australia (Centre of Research Excellence #1153176 and Career Development Fellowship #1108714); Jun Wang by grants from Shanghai Municipal Commission of Health and Family Planning (project number:2019SY032); and Peter B. Marschik was supported by the Bill and Melinda Gates Foundation Grand Challenges Exploration Grant (OPP 1128871).